GENETIC INHERITENCE PART-1 (GREGOR MENDEL& HIS EXPERIMENTS)

 

GENETIC INHERITANCE

Genetic inheritance is a basic principle of genetics and explains how characteristics are passed from one generation to the next.

Genetic inheritance occurs due to genetic material, in the form of DNA, being passed from parents to their offspring. When organisms reproduce, all the information for growth, survival, and reproduction for the next generation is found in the DNA passed down from the parent generation.

Much of our understanding of inheritance began with the work of a monk by the name of Gregor Mendel. His experiments and ‘Laws of Inheritance’ provide the foundations for modern genetics.

In sexual reproduction, the genetic material of two parents is combined and passed on to one individual. Although the offspring receives a combination of genetic material from two parents, certain genes from each parent will dominate the expression of different traits.

GREGOR MENDEL

Gregor Mendel was a monk and scientist and he is commonly referred to as the father of modern genetics. He completed a series of experiments looking at the inheritance of a number of characteristics in pea plants. Mendel published his work in 1865 (24 years before the word ‘gene’ was ever used) and the significance of his research was not appreciated until 1900, 16 years after his death.

Mendel is accredited as the first person to correctly understand the process of how characteristics are inherited by offspring from parents. Before Mendel, many other incorrect hypotheses attempted to explain how characteristics and traits were passed from generation to generation. The most commonly accepted theory was the ‘blending theory’ which proposed that the traits of parents were blended together and an intermediate trait was expressed in the offspring. Mendel’s work on the common pea plant proved that was not the case.

MENDEL’S EXPERIMENTS

Mendel performed a series of rigorous experiments that looked at 7 different characteristics (e.g. flower color, seed color, and seed shape), each with 2 different traits (e.g. purple flower and white flowers).

He established true-breeding lines for each characteristic. For example, one line of plants would produce only purple flowers and another only white. He then crossed individuals with two different traits to see the resulting trait of the offspring over three generations.

In his observations, Mendel found that in the first generation of offspring only one of the traits was ever expressed (e.g. purple flowers). After crossing the first generation of offspring with each other, Mendel found that approximately 75% of the second generation inherited the same trait as their parents (i.e. the purple flowers of the first generation of offspring). The remaining 25% expressed the second trait of the original parents (e.g. white flowers), the trait that appeared to be lost in the first generation of offspring.

MENDEL’S CONCLUSIONS

Following three generations of cross-breeding Mendel produced three significant conclusions regarding genetic inheritance. His first conclusion was that each trait is passed on unchanged to offspring via ‘units of inheritance’. These units are now known as ‘alleles’.

Mendel’s second conclusion, offspring inherit one allele from each parent for each characteristic. His third and final conclusion was that some alleles may not be expressed in an individual but can still be passed on to the next generation.

MENDEL’S LAWS OF INHERITANCE

• Law of Segregation – The alleles for each character segregate during gamete production so that each gamete will only have one of the two alleles for each gene.
• Law of Independent Assortment – Pairs of alleles for each characteristic/gene segregate independently of each other.

Mendel’s work has been heavily built upon over the past 150 years and the field of genetics has come a long way since his pea experiments. His work set the foundation for our understanding of genetic inheritance in animals, plants, and other complex organisms the process of inheritance is hugely important for understanding the complexity of life on Earth, in particular for its role in sexual reproduction and evolution. For this, Mendel’s contributions to science, biology, and genetics are still widely recognized and applauded within the scientific community..